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Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f4ff853717794cae9925e033f2dae11f

Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

About this item

Full title

Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

Publisher

London: Nature Publishing Group UK

Journal title

npj Regenerative medicine, 2023-08, Vol.8 (1), p.43-43, Article 43

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Transcription factor-based cellular reprogramming provides an attractive approach to produce desired cell types for regenerative medicine purposes. Such cellular conversions are widely dependent on viral vectors to efficiently deliver and express defined factors in target cells. However, use of viral vectors is associated with unfavorable genomic i...

Alternative Titles

Full title

Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f4ff853717794cae9925e033f2dae11f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f4ff853717794cae9925e033f2dae11f

Other Identifiers

ISSN

2057-3995

E-ISSN

2057-3995

DOI

10.1038/s41536-023-00317-z

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