Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
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England: Wellcome Trust Limited
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English
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England: Wellcome Trust Limited
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. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of 12/15-LOX to directly regulate B cell function has not been studied.
The influence of 1...
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Full title
Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_f5090539914842ae958ac2f738de381f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5090539914842ae958ac2f738de381f
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ISSN
2398-502X
E-ISSN
2398-502X
DOI
10.12688/wellcomeopenres.10308.1