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Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5090539914842ae958ac2f738de381f

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

About this item

Full title

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

Publisher

England: Wellcome Trust Limited

Journal title

Wellcome open research, 2017-01, Vol.2, p.1-1

Language

English

Formats

Publication information

Publisher

England: Wellcome Trust Limited

More information

Scope and Contents

Contents

. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of 12/15-LOX to directly regulate B cell function has not been studied.
The influence of 1...

Alternative Titles

Full title

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f5090539914842ae958ac2f738de381f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5090539914842ae958ac2f738de381f

Other Identifiers

ISSN

2398-502X

E-ISSN

2398-502X

DOI

10.12688/wellcomeopenres.10308.1

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