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The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by...

The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5292120853846b49db0b3417ba198cd

The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone

About this item

Full title

The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone

Publisher

England: John Wiley & Sons, Inc

Journal title

FEBS open bio, 2021-03, Vol.11 (3), p.578-587

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Electrostatic interactions between charged gatekeeper residues of the enzyme and approaching substrates can effectively discriminate between similar substrates. We investigated whether the charged gatekeeper residues play any role in the substrate specificity of P. falciparum succinyl‐CoA synthetase (PfSCS). Our results demonstrated that charged ga...

Alternative Titles

Full title

The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f5292120853846b49db0b3417ba198cd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5292120853846b49db0b3417ba198cd

Other Identifiers

ISSN

2211-5463

E-ISSN

2211-5463

DOI

10.1002/2211-5463.13034

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