TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy
TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Dysregulation of the balance between pro-inflammatory and anti-inflammatory macrophages has a key function in the pathogenesis of Duchenne muscular dystrophy (DMD), a fatal genetic disease. We postulate that an evolutionarily ancient protective mechanism against infection, known as trained immunity, drives pathological inflammation in DMD. Here we...
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TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy
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TN_cdi_doaj_primary_oai_doaj_org_article_f53cb28dfadf4338980346e7583e064c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f53cb28dfadf4338980346e7583e064c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28531-1
