Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation
Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation
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Author / Creator
Lu, Li , Zhitao, Li , Nannan, Cui , Mingzhu, Huang , Xiaoping, Hu , Dongsheng, Hong , Zongfu, Pan and Xiaoyang, Lu
Publisher
United States: Hindawi
Journal title
Language
English
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Publisher
United States: Hindawi
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Contents
β cell dysfunction is the leading cause of diabetes. Adult β cells have matured glucose-stimulated insulin secretion (GSIS), whereas fetal and neonatal β cells are insensitive to glucose and are functionally immature. However, how β cells mature and acquire robust GSIS is not fully understood. Here, we explored the potential regulatory proteins of...
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Full title
Mitofusin2 Promotes β Cell Maturation from Mouse Embryonic Stem Cells via Sirt3/Idh2 Activation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f54338edebdb42e1926947849de28d49
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f54338edebdb42e1926947849de28d49
Other Identifiers
ISSN
1687-966X,1687-9678
E-ISSN
1687-9678
DOI
10.1155/2022/1172795
