EGFR phosphorylates DNAJB1 to suppress α-synuclein aggregation in Parkinson’s disease
EGFR phosphorylates DNAJB1 to suppress α-synuclein aggregation in Parkinson’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Parkinson’s disease (PD), characterized by α-synuclein accumulation in dopaminergic neurons, is a common neurodegenerative disorder. Recent findings highlight DNAJB1 as a crucial factor in the disaggregation of α-synuclein fibrils in vitro, yet the underlying mechanisms and regulatory processes in neuronal cells remain largely undefined. This study...
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EGFR phosphorylates DNAJB1 to suppress α-synuclein aggregation in Parkinson’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_f54dbd2a82d540d8b74eb5bde21be24d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f54dbd2a82d540d8b74eb5bde21be24d
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ISSN
2373-8057
E-ISSN
2373-8057
DOI
10.1038/s41531-025-01006-y
