2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the...
2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the HIF1-α/SLC7A11 pathway
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Ferroptosis is a novel type of programmed cell death associated with lung injury induced by chronic intermittent hypoxia (CIH). 2-Methoxyestradiol (2-ME2), as an inhibitor of Hypoxia-inducible factor 1 alpha (HIF-1α), affects HIF-1α-related biological processes. This study aimed to explore the role and mechanism of 2-ME2 on CIH-induced lung injury....
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2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the HIF1-α/SLC7A11 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_f577c6f388cb4654911fb6eca5134307
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f577c6f388cb4654911fb6eca5134307
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-02675-8