The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Dia...
The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double transgenic mouse model, Akimba (
Ins2
Akita
xVEGF
+
/
−
), which demonstrates hyperglycemia, vascular hyperpermeability and neovascularization seen in the...
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Full title
The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_f5819ad73a044bfe965b05e365cb38eb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5819ad73a044bfe965b05e365cb38eb
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-21198-z
