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NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis...

NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f594003ec6fb4af3bfa3e8652fa34392

NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway

About this item

Full title

NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2023-06, Vol.21 (1), p.362-362, Article 362

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Reprogramming lipid metabolism for tumor metastasis is essential in breast cancer, and NUCB2/Nesfatin-1 plays a crucial role in regulating energy metabolism. Its high expression is associated with poor prognosis in breast cancer. Here, we studied whether NUCB2/Nesfatin-1 promotes breast cancer metastasis through reprogramming cholesterol metabolism...

Alternative Titles

Full title

NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f594003ec6fb4af3bfa3e8652fa34392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f594003ec6fb4af3bfa3e8652fa34392

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-023-04236-x

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