NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis...
NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway
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Author / Creator
Ning, Siyi , Liu, Caiying , Wang, Kangtao , Cai, Yubo , Ning, Zhicheng , Li, Ming and Zeng, Liang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Reprogramming lipid metabolism for tumor metastasis is essential in breast cancer, and NUCB2/Nesfatin-1 plays a crucial role in regulating energy metabolism. Its high expression is associated with poor prognosis in breast cancer. Here, we studied whether NUCB2/Nesfatin-1 promotes breast cancer metastasis through reprogramming cholesterol metabolism...
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Full title
NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f594003ec6fb4af3bfa3e8652fa34392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f594003ec6fb4af3bfa3e8652fa34392
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-04236-x