A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein F...
A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein Families
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Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Naturally occurring echinocandin B and FR901379 are potent antifungal lipopeptides featuring a cyclic hexapeptide nucleus and a fatty acid side chain. They are the parent compounds of echinocandin drugs for the treatment of severe fungal infections caused by the Candida and Aspergilla species. To minimize hemolytic toxicity, the native fatty acid s...
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Full title
A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein Families
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_f5a9d92459764ffca8c3e843fef07bd5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5a9d92459764ffca8c3e843fef07bd5
Other Identifiers
ISSN
1660-3397
E-ISSN
1660-3397
DOI
10.3390/md22050212
