Identification of novel leads as potent inhibitors of HDAC3 using ligand-based pharmacophore modelin...
Identification of novel leads as potent inhibitors of HDAC3 using ligand-based pharmacophore modeling and MD simulation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In the landscape of epigenetic regulation, histone deacetylase 3 (HDAC3) has emerged as a prominent therapeutic target for the design and development of candidate drugs against various types of cancers and other human disorders. Herein, we have performed ligand-based pharmacophore modeling, virtual screening, molecular docking, and MD simulations t...
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Identification of novel leads as potent inhibitors of HDAC3 using ligand-based pharmacophore modeling and MD simulation
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TN_cdi_doaj_primary_oai_doaj_org_article_f5b5283a2985486dae8d0b911a30568b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5b5283a2985486dae8d0b911a30568b
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-05698-7
