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Systematic identification of cis-regulatory variants that cause gene expression differences in a yea...

Systematic identification of cis-regulatory variants that cause gene expression differences in a yea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5c445c8c15c479b999e7a92cbb6424a

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross

About this item

Full title

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross

Publisher

England: eLife Sciences Publications, Ltd

Journal title

eLife, 2020-11, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

Sequence variation in regulatory DNA alters gene expression and shapes genetically complex traits. However, the identification of individual, causal regulatory variants is challenging. Here, we used a massively parallel reporter assay to measure the
cis
-regulatory consequences of 5832 natural DNA variants in the promoters of 2503 genes in th...

Alternative Titles

Full title

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f5c445c8c15c479b999e7a92cbb6424a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5c445c8c15c479b999e7a92cbb6424a

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.62669

How to access this item