Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticul...
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress
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Author / Creator
Wu, Yunhao , Meng, Wei , Guan, Ming , Zhao, Xiaolong , Zhang, Chen , Fang, Qiaojun , Zhang, Yuhua , Sun, Zihui , Cai, Mingjing , Huang, Dongdong , Yang, Xuechun , Yu, Yafeng , Cui, Yong , He, Shuangba and Chai, Renjie
Publisher
Lausanne: Frontiers Research Foundation
Journal title
Language
English
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Publisher
Lausanne: Frontiers Research Foundation
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Contents
Irreversible injury to inner ear hair cells induced by aminoglycoside antibiotics contributes to the formation of sensorineural hearing loss. Pitavastatin (PTV), a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, has been reported to exert neuroprotective effects. However, its role in aminoglycoside-induced hearing loss remains unknown. T...
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Full title
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress
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TN_cdi_doaj_primary_oai_doaj_org_article_f5e5c13afb4b418cb25f4dd1e005a9fd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f5e5c13afb4b418cb25f4dd1e005a9fd
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2022.963083
