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Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models...

Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6002cc832d14136abf6f7b427ad84fe

Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy

About this item

Full title

Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy

Publisher

United States: John Wiley & Sons, Inc

Journal title

Cancer Communications, 2024-01, Vol.44 (1), p.178-182

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

[...]selective blocking of these receptors can change the immune cell distribution towards CD8+ immune-competent cell lines. [...]we interbred compound KC mouse mutants with IL-6 knockout allele (Il-6−/−) or the conditional Cxcl12lox/+ allele and analyzed the distribution of immune cells in the pancreas (Supplementary Figure S8A-C). [...]the CD8+:C...

Alternative Titles

Full title

Dynamics and cytokinic regulation of immune cell infiltration in genetically engineered mouse models of pancreatic cancer dictate the sensitivity to immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f6002cc832d14136abf6f7b427ad84fe

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6002cc832d14136abf6f7b427ad84fe

Other Identifiers

ISSN

2523-3548

E-ISSN

2523-3548

DOI

10.1002/cac2.12496

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