27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human d...
27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Accumulation of the α-synuclein (α-syn) protein is a hallmark of a group of brain disorders collectively known as synucleinopathies. The mechanisms responsible for α-syn accumulation are not well understood. Several studies suggest a link between synucleinopathies and the cholesterol metabolite 27-hydroxycholesterol (27-OHC). 27-OHC is the major ch...
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Full title
27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_f60f57a0a347479491425c80dbcdba18
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f60f57a0a347479491425c80dbcdba18
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ISSN
1471-2202
E-ISSN
1471-2202
DOI
10.1186/s12868-018-0420-5
