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Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potentia...

Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potentia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f627979531de426780a51efa1be9b801

Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

About this item

Full title

Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

Publisher

Switzerland: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2023-04, Vol.13 (4), p.686

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Closely associated with aging and age-related disorders, cellular senescence (CS) is the inability of cells to proliferate due to accumulated unrepaired cellular damage and irreversible cell cycle arrest. Senescent cells are characterized by their senescence-associated secretory phenotype that overproduces inflammatory and catabolic factors that ha...

Alternative Titles

Full title

Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f627979531de426780a51efa1be9b801

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f627979531de426780a51efa1be9b801

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom13040686

How to access this item