WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
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England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Self-organization of discrete fates in human gastruloids is mediated by a hierarchy of signaling pathways. How these pathways are integrated in time, and whether cells maintain a memory of their signaling history remains obscure. Here, we dissect the temporal integration of two key pathways, WNT and ACTIVIN, which along with BMP control gastrulatio...
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Full title
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
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TN_cdi_doaj_primary_oai_doaj_org_article_f63cd96773234a5c94c1350230c6fbcc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f63cd96773234a5c94c1350230c6fbcc
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.38279
