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METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease throu...

METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease throu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f66fe5d561794f0b98d55fb3390406cd

METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events

About this item

Full title

METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events

Publisher

London: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2021-09, Vol.16 (1), p.1-25, Article 70

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background N6-methyladenosine (m.sup.6A) modification of RNA influences fundamental aspects of RNA metabolism and m.sup.6A dysregulation is implicated in various human diseases. In this study, we explored the potential role of RNA m.sup.6A modification in the pathogenesis of Alzheimer disease (AD). Methods We investigated the m.sup.6A modification...

Alternative Titles

Full title

METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer’s disease through aberrant cell cycle events

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f66fe5d561794f0b98d55fb3390406cd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f66fe5d561794f0b98d55fb3390406cd

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-021-00484-x

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