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Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f68a51d6e42349948384f58cf1f57479

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

About this item

Full title

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2018-04, Vol.10 (4), p.1-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges. Deregulated receptor tyrosine kinase (RTK) signalling mediated by loss of tumour suppressor Sprouty2 (SPRY2) is associated with treatment resistance. Using pre‐clinical human and murine mCRPC...

Alternative Titles

Full title

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f68a51d6e42349948384f58cf1f57479

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f68a51d6e42349948384f58cf1f57479

Other Identifiers

ISSN

1757-4676,1757-4684

E-ISSN

1757-4684

DOI

10.15252/emmm.201708347

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