Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges. Deregulated receptor tyrosine kinase (RTK) signalling mediated by loss of tumour suppressor Sprouty2 (SPRY2) is associated with treatment resistance. Using pre‐clinical human and murine mCRPC...
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Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
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TN_cdi_doaj_primary_oai_doaj_org_article_f68a51d6e42349948384f58cf1f57479
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f68a51d6e42349948384f58cf1f57479
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ISSN
1757-4676,1757-4684
E-ISSN
1757-4684
DOI
10.15252/emmm.201708347