Cluster effect for SNP–SNP interaction pairs for predicting complex traits
Cluster effect for SNP–SNP interaction pairs for predicting complex traits
About this item
Full title
Author / Creator
Lin, Hui-Yi , Mazumder, Harun , Sarkar, Indrani , Huang, Po-Yu , Eeles, Rosalind A. , Kote-Jarai, Zsofia , Muir, Kenneth R. , Schleutker, Johanna , Pashayan, Nora , Batra, Jyotsna , Neal, David E. , Nielsen, Sune F. , Nordestgaard, Børge G. , Grönberg, Henrik , Wiklund, Fredrik , MacInnis, Robert J. , Haiman, Christopher A. , Travis, Ruth C. , Stanford, Janet L. , Kibel, Adam S. , Cybulski, Cezary , Khaw, Kay-Tee , Maier, Christiane , Thibodeau, Stephen N. , Teixeira, Manuel R. , Cannon-Albright, Lisa , Brenner, Hermann , Kaneva, Radka , Pandha, Hardev , Park, Jong Y. , UKGPCS collaborators , APCB (Australian Prostate Cancer BioResource) , The PRACTICAL consortium and PRACTICAL consortium
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Single nucleotide polymorphism (SNP) interactions are the key to improving polygenic risk scores. Previous studies reported several significant SNP–SNP interaction pairs that shared a common SNP to form a cluster, but some identified pairs might be false positives. This study aims to identify factors associated with the cluster effect of false posi...
Alternative Titles
Full title
Cluster effect for SNP–SNP interaction pairs for predicting complex traits
Authors, Artists and Contributors
Author / Creator
Mazumder, Harun
Sarkar, Indrani
Huang, Po-Yu
Eeles, Rosalind A.
Kote-Jarai, Zsofia
Muir, Kenneth R.
Schleutker, Johanna
Pashayan, Nora
Batra, Jyotsna
Neal, David E.
Nielsen, Sune F.
Nordestgaard, Børge G.
Grönberg, Henrik
Wiklund, Fredrik
MacInnis, Robert J.
Haiman, Christopher A.
Travis, Ruth C.
Stanford, Janet L.
Kibel, Adam S.
Cybulski, Cezary
Khaw, Kay-Tee
Maier, Christiane
Thibodeau, Stephen N.
Teixeira, Manuel R.
Cannon-Albright, Lisa
Brenner, Hermann
Kaneva, Radka
Pandha, Hardev
Park, Jong Y.
UKGPCS collaborators
APCB (Australian Prostate Cancer BioResource)
The PRACTICAL consortium
PRACTICAL consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f6d6e2ec91c84df5bee4f5f2c347d676
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6d6e2ec91c84df5bee4f5f2c347d676
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-66311-7
