Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution
Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Label-free detection of single-nucleotides was performed by fast tunneling current measurements in a polar solvent at 1 MHz sampling rate using SiO2-protected Au nanoprobes. Short current spikes were observed, suggestive of trapping/detrapping of individual nucleotides between the nanoelectrodes. The fall and rise features of the electrical signatu...
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Full title
Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution
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TN_cdi_doaj_primary_oai_doaj_org_article_f6e5967259d447bcb4fb93b46894bbf8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f6e5967259d447bcb4fb93b46894bbf8
Other Identifiers
ISSN
1424-8220
E-ISSN
1424-8220
DOI
10.3390/s17040885
