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Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine...

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f709a55fc0cc4c0b854e870ae4c8e741

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm

About this item

Full title

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-11, Vol.12 (1), p.6645-19, Article 6645

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The poles of the heart and branchiomeric muscles of the face and neck are formed from the cardiopharyngeal mesoderm within the pharyngeal apparatus. They are disrupted in patients with 22q11.2 deletion syndrome, due to haploinsufficiency of
TBX1
, encoding a T-box transcription factor. Here, using single cell RNA-sequencing, we now identify a...

Alternative Titles

Full title

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f709a55fc0cc4c0b854e870ae4c8e741

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f709a55fc0cc4c0b854e870ae4c8e741

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-26966-6

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