Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithel...
Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithelial cells in lupus nephritis through the NLRP3/IL-33/ST2 axis
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Author / Creator
Ma, Qing , Xu, Mengyang , Jing, Xin , Qiu, Jiang , Huang, Shuo , Yan, Honghao , Yin, Lu , Lou, Jiang , Zhao, Lisha , Fan, Yongsheng and Qiu, Ping
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lupus nephritis (LN) is a type of immune-complex nephritis caused by systemic lupus erythematosus and is a major contributor to mortality and morbidity. Honokiol (HNK) has been found to have a therapeutic effect on LN, but its action mechanism remains unclear. In this study, we first demonstrated that HNK attenuates kidney injury in MRL/lpr mice. R...
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Full title
Honokiol suppresses the aberrant interactions between renal resident macrophages and tubular epithelial cells in lupus nephritis through the NLRP3/IL-33/ST2 axis
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TN_cdi_doaj_primary_oai_doaj_org_article_f71a841ab7a74dc7816cbdb1eb554183
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f71a841ab7a74dc7816cbdb1eb554183
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05680-9
