Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential...
Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells
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Author / Creator
Parodi, Monica , Centonze, Giovanni , Murianni, Fabio , Orecchia, Paola , Andriani, Francesca , Roato, Ilaria , Gardelli, Cecilia , Balsamo, Melissa , Moro, Massimo , Taiè, Giulia , Pastorino, Ugo , Petretto, Andrea , Lavarello , Chiara , Milione, Massimo , Sozzi, Gabriella , Roz, Luca , Vitale, Massimo and Bertolini, Giulia
Publisher
England: BMJ Publishing Group Ltd
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Language
English
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England: BMJ Publishing Group Ltd
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BackgroundEpithelial to mesenchymal transition (EMT) endows cancer cells with pro-metastatic properties, which appear most effective when cells enter an intermediate hybrid (H) state, characterized by integrated mesenchymal (M) and epithelial (E) traits. The reasons for this advantage are poorly known and, especially, it is totally unexplored wheth...
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Full title
Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells
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TN_cdi_doaj_primary_oai_doaj_org_article_f72425c485344776a7a4043b68dafea4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f72425c485344776a7a4043b68dafea4
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2023-007895