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Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid...

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f736b737ff18458391da2cc5d0a70964

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

About this item

Full title

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

Publisher

England: BioMed Central Ltd

Journal title

Biomarker research, 2022-04, Vol.10 (1), p.16-16, Article 16

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful use of vitamin D (1,25VD3) gene therapy to treat AML mouse models in vivo. In this study, recognizing the imp...

Alternative Titles

Full title

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f736b737ff18458391da2cc5d0a70964

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f736b737ff18458391da2cc5d0a70964

Other Identifiers

ISSN

2050-7771

E-ISSN

2050-7771

DOI

10.1186/s40364-022-00367-3

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