A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabe...
A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients
About this item
Full title
Author / Creator
Giraudet, Anne-Laure , Cassier, Philippe Alexandre , Iwao-Fukukawa, Chicaco , Garin, Gwenaelle , Badel, Jean-Noël , Kryza, David , Chabaud, Sylvie , Gilles-Afchain, Laurence , Clapisson, Gilles , Desuzinges, Claude , Sarrut, David , Halty, Adrien , Italiano, Antoine , Mori, Masaharu , Tsunoda, Takuya , Katagiri, Toyomasa , Nakamura, Yusuke , Alberti, Laurent , Cropet, Claire , Baconnier, Simon , Berge-Montamat, Sandrine , Pérol, David and Blay, Jean-Yves
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Synovial Sarcomas (SS) are rare tumors occurring predominantly in adolescent and young adults with a dismal prognosis in advanced phases. We report a first-in-human phase I of monoclonal antibody (OTSA-101) targeting FZD10, overexpressed in most SS but not present in normal tissues, labelled with radioisotopes and used as a molecular vehicle to spe...
Alternative Titles
Full title
A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients
Authors, Artists and Contributors
Author / Creator
Cassier, Philippe Alexandre
Iwao-Fukukawa, Chicaco
Garin, Gwenaelle
Badel, Jean-Noël
Kryza, David
Chabaud, Sylvie
Gilles-Afchain, Laurence
Clapisson, Gilles
Desuzinges, Claude
Sarrut, David
Halty, Adrien
Italiano, Antoine
Mori, Masaharu
Tsunoda, Takuya
Katagiri, Toyomasa
Nakamura, Yusuke
Alberti, Laurent
Cropet, Claire
Baconnier, Simon
Berge-Montamat, Sandrine
Pérol, David
Blay, Jean-Yves
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f7e4c42b865f4a648c225b6c01e4f105
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7e4c42b865f4a648c225b6c01e4f105
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-018-4544-x
