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Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7edb1aa7e034097bfaeab285876053f

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

About this item

Full title

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-04, Vol.10 (1), p.1911-13, Article 1911

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Multiple myeloma is a malignancy of antibody-secreting plasma cells. Most patients benefit from current therapies, however, 20% of patients relapse or die within two years and are deemed high risk. Here we analyze structural variants from 795 newly-diagnosed patients as part of the CoMMpass study. We report translocations involving the immunoglobul...

Alternative Titles

Full title

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f7edb1aa7e034097bfaeab285876053f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7edb1aa7e034097bfaeab285876053f

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-09555-6

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