A dual role of HIF1α in regulating osteogenesis-angiogenesis coupling
A dual role of HIF1α in regulating osteogenesis-angiogenesis coupling
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England: BioMed Central
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English
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England: BioMed Central
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The hypoxia-inducible factor 1-α (HIF1α), a key molecule in mediating bone-vessel crosstalk, has been considered a promising target for treating osteoporosis caused by gonadal hormones. However, senile osteoporosis, with accumulated senescent cells in aged bone, has a distinct pathogenesis. The study aimed at revealing the unknown role of HIF1α in...
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A dual role of HIF1α in regulating osteogenesis-angiogenesis coupling
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TN_cdi_doaj_primary_oai_doaj_org_article_f7f13c18251b44509688eb0422843bdd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7f13c18251b44509688eb0422843bdd
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-022-02742-1