Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL throug...
Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
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Author / Creator
Sun, Qi , Lu, Zhihua , Zhang, Yanpeng , Xue, Dong , Xia, Huayu , She, Junjun and Li, Fanni
Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
Integrin β3 plays a key role in the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI), but the development of integrin β3 inhibitors has been stalled due to the failure of phase III clinical trials for cancer treatment. Therefore, it is imperative to find a potentially effective solution to the problem of acquired...
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Full title
Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_f7f532959b3f46919018ae4cdcf8ebc6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f7f532959b3f46919018ae4cdcf8ebc6
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11132078