The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker...
The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Accumulating evidence suggests that dysregulation of transcriptional enhancers plays a significant role in cancer pathogenesis. Herein, we performed a genome-wide discovery of enhancer elements in colorectal cancer (CRC). We identified
PVT1
locus as a previously unrecognized transcriptional regulator in CRC with a significantly high enhancer...
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The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_f81d5d329eca4757ab0d4e06d2c236db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f81d5d329eca4757ab0d4e06d2c236db
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-020-01277-4
