Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purk...
Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purkinje cells
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Contents
Protein kinase C γ (PKCγ), a neuronal isoform present exclusively in the central nervous system, is most abundantly expressed in cerebellar Purkinje cells (PCs). Targeted deletion of PKCγ causes a climbing fiber synapse elimination in developing PCs and motor deficit. However, physiological roles of PKCγ in adult mouse PCs are little understood. In...
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Full title
Protein kinase Cγ negatively regulates the intrinsic excitability in zebrin-negative cerebellar Purkinje cells
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TN_cdi_doaj_primary_oai_doaj_org_article_f83b2856c047493d899fdaba4502e8cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f83b2856c047493d899fdaba4502e8cb
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2024.1349878
