SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia
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Luo, Yu-Wei , Zhou, Jiang-Peng , Ji, Hongyu , Xu, Doudou , Zheng, Anqi , Wang, Xin , Dai, Zhizheng , Luo, Zhicheng , Cao, Fang , Wang, Xing-Yue , Bai, Yunfang , Chen, Di , Chen, Yueming , Wang, Qi , Yang, Yaying , Zhang, Xinghai , Chiu, Sandra , Peng, Xiaozhong , Huang, Ai-Long and Tang, Kai-Fu
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Though RNAi and RNA-splicing machineries are involved in regulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication, their precise roles in coronavirus disease 2019 (COVID-19) pathogenesis remain unclear. Herein, we show that decreased RNAi component (Dicer and XPO5) and splicing factor (SRSF3 and hnRNPA3) expression correl...
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SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia
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TN_cdi_doaj_primary_oai_doaj_org_article_f83c917208ab46a9a59cbbe95dea9496
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f83c917208ab46a9a59cbbe95dea9496
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51192-1