Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev bi...
Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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During HIV infection, specific RNA-protein interaction between the Rev response element (RRE) and viral Rev protein is required for nuclear export of intron-containing viral mRNA transcripts. Rev initially binds the high-affinity site in stem-loop II, which promotes oligomerization of additional Rev proteins on RRE. Here, we present the crystal str...
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Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site
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TN_cdi_doaj_primary_oai_doaj_org_article_f858a5657fb84fe398c755927e4afd6d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f858a5657fb84fe398c755927e4afd6d
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48162-y
