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Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f8f04aa15ba940f9b5b72b1ccab92464

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

About this item

Full title

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2017-12, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways interact to maintain homeostasis in proliferating human cells, using fluorescent reporters for AMPK...

Alternative Titles

Full title

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f8f04aa15ba940f9b5b72b1ccab92464

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f8f04aa15ba940f9b5b72b1ccab92464

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.27293

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