The oncogenic fusion protein TAZ::CAMTA1 promotes genomic instability and senescence through hypertr...
The oncogenic fusion protein TAZ::CAMTA1 promotes genomic instability and senescence through hypertranscription
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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TAZ::CAMTA1 is a fusion protein found in over 90% of Epithelioid Hemangioendothelioma (EHE), a rare vascular sarcoma with an unpredictable disease course. To date, how TAZ::CAMTA1 initiates tumour formation remains unexplained. To study the oncogenic mechanism leading to EHE initiation, we developed a model system whereby TAZ::CAMTA1 expression is...
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The oncogenic fusion protein TAZ::CAMTA1 promotes genomic instability and senescence through hypertranscription
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TN_cdi_doaj_primary_oai_doaj_org_article_f8f5c01d0099483396ec497c3588065b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f8f5c01d0099483396ec497c3588065b
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2399-3642
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2399-3642
DOI
10.1038/s42003-023-05540-4