A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatr...
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML
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Author / Creator
Drenberg, Christina D. , Shelat, Anang , Dang, Jinjun , Cotton, Anitria , Orwick, Shelley J. , Li, Mengyu , Jeon, Jae Yoon , Fu, Qiang , Buelow, Daelynn R. , Pioso, Marissa , Hu, Shuiying , Inaba, Hiroto , Ribeiro, Raul C. , Rubnitz, Jeffrey E. , Gruber, Tanja A. , Guy, R. Kiplin and Baker, Sharyn D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Improvement in survival has been achieved for children and adolescents with AML but is largely attributed to enhanced supportive care as opposed to the development of better treatment regimens. High risk subtypes continue to have poor outcomes with event free survival rates <40% despite the use of high intensity chemotherapy in combination with hem...
Alternative Titles
Full title
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f909cbdab341455d9f702b6081a46e6f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f909cbdab341455d9f702b6081a46e6f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09917-0
