Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple...
Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
The current literature on single cell genomic analyses on the DNA level is conflicting regarding requirements for cell quality, amplification success rates, allelic dropouts and resolution, lacking a systematic comparison of multiple cell input down to the single cell. We hypothesized that such a correlation assay would provide an approach to addre...
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Full title
Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing
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TN_cdi_doaj_primary_oai_doaj_org_article_f9324b4dc0d94ba3be4b888025d15cfc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9324b4dc0d94ba3be4b888025d15cfc
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-018-5063-5
