Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell in the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive caspases, including caspases 3 and 7, play critical roles in apoptosis. The effects of the ablation of the...
Alternative Titles
Full title
Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f961223280f14377aa6cb072779c39eb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f961223280f14377aa6cb072779c39eb
Other Identifiers
ISSN
0717-6287,0716-9760
E-ISSN
0717-6287
DOI
10.1186/s40659-020-00319-x
