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Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9992a0e71944714947dfcccc820b5a8

Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

About this item

Full title

Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

Publisher

London: Nature Publishing Group UK

Journal title

Cell death discovery, 2021-10, Vol.7 (1), p.310-310, Article 310

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Heart failure (HF) has reached epidemic proportions in developed countries, affecting over 20 million people worldwide. Despite modern medical and device therapies, 60–70% of HF patients still die within 5 years of diagnosis as it relentlessly progresses through pervasive apoptotic loss of cardiomyocytes. Although fortilin, a 172-amino-acid anti-p5...

Alternative Titles

Full title

Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f9992a0e71944714947dfcccc820b5a8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9992a0e71944714947dfcccc820b5a8

Other Identifiers

ISSN

2058-7716

E-ISSN

2058-7716

DOI

10.1038/s41420-021-00692-w

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