MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation
MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation
About this item
Full title
Author / Creator
Schaefer, Inga-Marie , Wang, Yuexiang , Liang, Cher-wei , Bahri, Nacef , Quattrone, Anna , Doyle, Leona , Mariño-Enríquez, Adrian , Lauria, Alexandra , Zhu, Meijun , Debiec-Rychter, Maria , Grunewald, Susanne , Hechtman, Jaclyn F. , Dufresne, Armelle , Antonescu, Cristina R. , Beadling, Carol , Sicinska, Ewa T. , van de Rijn, Matt , Demetri, George D. , Ladanyi, Marc , Corless, Christopher L. , Heinrich, Michael C. , Raut, Chandrajit P. , Bauer, Sebastian and Fletcher, Jonathan A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
KIT
,
PDGFRA
,
NF1
and
SDH
mutations are alternate initiating events, fostering hyperplasia in gastrointestinal stromal tumours (GISTs), and additional genetic alterations are required for progression to malignancy. The most frequent secondary alteration, demonstrated in ∼70% of GISTs, is chromosome 14q deletion. Here we report...
Alternative Titles
Full title
MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation
Authors, Artists and Contributors
Author / Creator
Wang, Yuexiang
Liang, Cher-wei
Bahri, Nacef
Quattrone, Anna
Doyle, Leona
Mariño-Enríquez, Adrian
Lauria, Alexandra
Zhu, Meijun
Debiec-Rychter, Maria
Grunewald, Susanne
Hechtman, Jaclyn F.
Dufresne, Armelle
Antonescu, Cristina R.
Beadling, Carol
Sicinska, Ewa T.
van de Rijn, Matt
Demetri, George D.
Ladanyi, Marc
Corless, Christopher L.
Heinrich, Michael C.
Raut, Chandrajit P.
Bauer, Sebastian
Fletcher, Jonathan A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f99b7b0f7dfb4944b7bbfdf9272bbf4d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f99b7b0f7dfb4944b7bbfdf9272bbf4d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14674
