The mammalian PYHIN gene family: Phylogeny, evolution and expression
The mammalian PYHIN gene family: Phylogeny, evolution and expression
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Proteins of the mammalian PYHIN (IFI200/HIN-200) family are involved in defence against infection through recognition of foreign DNA. The family member absent in melanoma 2 (AIM2) binds cytosolic DNA via its HIN domain and initiates inflammasome formation via its pyrin domain. AIM2 lies within a cluster of related genes, many of which are uncharact...
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Full title
The mammalian PYHIN gene family: Phylogeny, evolution and expression
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TN_cdi_doaj_primary_oai_doaj_org_article_f9b4b33f29694f79a0ac6e47ac23c04b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9b4b33f29694f79a0ac6e47ac23c04b
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ISSN
1471-2148
E-ISSN
1471-2148
DOI
10.1186/1471-2148-12-140
