STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Signal transducer and activator of transcription 3 (STAT3), a multifaceted transcription factor, modulates host immune responses by activating cellular response to signaling ligands. STAT3 has a pivotal role in the pathophysiology of kidney injury by counterbalancing resident macrophage phenotypes under inflammation conditions. However, STAT3's rol...
Alternative Titles
Full title
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation
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TN_cdi_doaj_primary_oai_doaj_org_article_f9bcd320f61845f7955080126070edc6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9bcd320f61845f7955080126070edc6
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-024-01841-1
