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Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9c5fcf1b41543b299f0dd8f3efb65c3

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

About this item

Full title

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

Publisher

Abingdon: Taylor & Francis Ltd

Journal title

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.1987-1994

Language

English

Formats

Publication information

Publisher

Abingdon: Taylor & Francis Ltd

More information

Scope and Contents

Contents

We have recently developed a new synthetic methodology that provided both N-aryl-5-hydroxytriazoles and N-pyridine-4-alkyl triazoles. A selection of these products was carried through virtual screening towards targets that are contemporary and validated for drug discovery and development. This study determined a number of potential structure target...

Alternative Titles

Full title

Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_f9c5fcf1b41543b299f0dd8f3efb65c3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9c5fcf1b41543b299f0dd8f3efb65c3

Other Identifiers

ISSN

1475-6366

E-ISSN

1475-6374

DOI

10.1080/14756366.2022.2097447

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