Identification of small molecules affecting the interaction between human hemoglobin and Staphylococ...
Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore
About this item
Full title
Author / Creator
Cozzi, Monica , Failla, Mariacristina , Gianquinto, Eleonora , Kovachka, Sandra , Buoli Comani, Valeria , Compari, Carlotta , De Bei, Omar , Giaccari, Roberta , Marchesani, Francesco , Marchetti, Marialaura , Ronda, Luca , Rolando, Barbara , Baroni, Massimo , Cruciani, Gabriele , Campanini, Barbara , Bettati, Stefano , Faggiano, Serena , Lazzarato, Loretta and Spyrakis, Francesca
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Human hemoglobin (Hb) is the preferred iron source of
Staphylococcus aureus
. This pathogenic bacterium exploits a sophisticated protein machinery called Iron-regulated surface determinant (Isd) system to bind Hb, extract and internalize heme, and finally degrade it to complete iron acquisition. IsdB, the surface exposed Hb receptor, is a pro...
Alternative Titles
Full title
Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore
Authors, Artists and Contributors
Author / Creator
Failla, Mariacristina
Gianquinto, Eleonora
Kovachka, Sandra
Buoli Comani, Valeria
Compari, Carlotta
De Bei, Omar
Giaccari, Roberta
Marchesani, Francesco
Marchetti, Marialaura
Ronda, Luca
Rolando, Barbara
Baroni, Massimo
Cruciani, Gabriele
Campanini, Barbara
Bettati, Stefano
Faggiano, Serena
Lazzarato, Loretta
Spyrakis, Francesca
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_f9ef68fdb4844b4a8556175d108cfb76
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9ef68fdb4844b4a8556175d108cfb76
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-55931-8
