Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculatur...
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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As we age, our body experiences chronic, systemic inflammation contributing to the morbidity and mortality of the elderly. The senescent immune system has been described to have a causal role in driving systemic aging and therefore may represent a key therapeutic target to prevent pathological consequences associated with aging and extend a healthy...
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Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline
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TN_cdi_doaj_primary_oai_doaj_org_article_f9f13f759a78476a87e24953bd0cf51e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_f9f13f759a78476a87e24953bd0cf51e
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04535-z
