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Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa076134ba1d4bf2a890c2226b76f5d5

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

About this item

Full title

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-05, Vol.12 (1), p.7273-14, Article 7273

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents reduces body weight and improves insulin sensitivity and ass...

Alternative Titles

Full title

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fa076134ba1d4bf2a890c2226b76f5d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa076134ba1d4bf2a890c2226b76f5d5

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-11219-3

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