Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
About this item
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Author / Creator
Li, Ying , Talbot, Chad Lamar , Chandravanshi, Bhawna , Ksiazek, Alec , Sood, Ayushi , Chowdhury, Kamrul Hasan , Maschek, J. Alan , Cox, James , Babu, Adhini Kuppuswamy Satheesh , Paz, Henry A. , Babu, Pon Velayutham Anandh , Meyerholz, David K. , Wankhade, Umesh D. , Holland, William , Shyong Tai, E. , Summers, Scott A. and Chaurasia, Bhagirath
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents reduces body weight and improves insulin sensitivity and ass...
Alternative Titles
Full title
Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
Authors, Artists and Contributors
Author / Creator
Talbot, Chad Lamar
Chandravanshi, Bhawna
Ksiazek, Alec
Sood, Ayushi
Chowdhury, Kamrul Hasan
Maschek, J. Alan
Cox, James
Babu, Adhini Kuppuswamy Satheesh
Paz, Henry A.
Babu, Pon Velayutham Anandh
Meyerholz, David K.
Wankhade, Umesh D.
Holland, William
Shyong Tai, E.
Summers, Scott A.
Chaurasia, Bhagirath
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fa076134ba1d4bf2a890c2226b76f5d5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa076134ba1d4bf2a890c2226b76f5d5
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-11219-3