A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leuk...
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia
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Author / Creator
Edtmayer, Sophie , Witalisz-Siepracka, Agnieszka , Zdársky, Bernhard , Heindl, Kerstin , Weiss, Stefanie , Eder, Thomas , Dutta, Sayantanee , Graichen, Uwe , Klee, Sascha , Sharif, Omar , Wieser, Rotraud , Győrffy, Balázs , Poli, Valeria , Casanova, Emilio , Sill, Heinz , Grebien, Florian and Stoiber, Dagmar
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Signal transducer and activator of transcription 3 (STAT3) is frequently overexpressed in patients with acute myeloid leukemia (AML). STAT3 exists in two distinct alternatively spliced isoforms, the full-length isoform STAT3α and the C-terminally truncated isoform STAT3β. While STAT3α is predominantly described as an oncogenic driver, STAT3β has be...
Alternative Titles
Full title
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_fa3588b01db84ae4a00ac9b61c021e7a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa3588b01db84ae4a00ac9b61c021e7a
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06749-9
