Sulforaphane enhances the antitumor response of chimeric antigen receptor T cells by regulating PD-1...
Sulforaphane enhances the antitumor response of chimeric antigen receptor T cells by regulating PD-1/PD-L1 pathway
About this item
Full title
Author / Creator
Shen, Chunyi , Zhang, Zhen , Tian, Yonggui , Li, Feng , Zhou, Lingxiao , Jiang, Wenyi , Yang, Li , Zhang, Bin , Wang, Liping and Zhang, Yi
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Chimeric antigen receptor T (CAR-T) cell therapy has limited effects in the treatment of solid tumors. Sulforaphane (SFN) is known to play an important role in inhibiting tumor growth, but its effect on CAR-T cells remains unclear. The goal of the current study was to determine whether combined CAR-T cells and SFN could provide antitumor efficacy a...
Alternative Titles
Full title
Sulforaphane enhances the antitumor response of chimeric antigen receptor T cells by regulating PD-1/PD-L1 pathway
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fa4414bc3272439a9714929ad02b2689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa4414bc3272439a9714929ad02b2689
Other Identifiers
ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-021-02161-8
