Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection...
Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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The striatum is involved in action selection, and its disturbance can cause movement disorders. Here, we show that leucine-rich repeats and transmembrane domain 2 (Lrtm2) controls protein sorting in striatal projection systems, and its deficiency causes disturbances in monoamine dynamics and behavior. The Lrtm2 protein was broadly detected in the b...
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Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics
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TN_cdi_doaj_primary_oai_doaj_org_article_fa4b4d5bba87434b9ad26127ce23e552
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa4b4d5bba87434b9ad26127ce23e552
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2022.856315
