Differentiation but not ALS mutations in FUS rewires motor neuron metabolism
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism
About this item
Full title
Author / Creator
Vandoorne, Tijs , Veys, Koen , Guo, Wenting , Sicart, Adria , Vints, Katlijn , Swijsen, Ann , Moisse, Matthieu , Eelen, Guy , Gounko, Natalia V. , Fumagalli, Laura , Fazal, Raheem , Germeys, Christine , Quaegebeur, Annelies , Fendt, Sarah-Maria , Carmeliet, Peter , Verfaillie, Catherine , Van Damme, Philip , Ghesquière, Bart , De Bock, Katrien and Van Den Bosch, Ludo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Energy metabolism has been repeatedly linked to amyotrophic lateral sclerosis (ALS). Yet, motor neuron (MN) metabolism remains poorly studied and it is unknown if ALS MNs differ metabolically from healthy MNs. To address this question, we first performed a metabolic characterization of induced pluripotent stem cells (iPSCs) versus iPSC-derived MNs...
Alternative Titles
Full title
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism
Authors, Artists and Contributors
Author / Creator
Veys, Koen
Guo, Wenting
Sicart, Adria
Vints, Katlijn
Swijsen, Ann
Moisse, Matthieu
Eelen, Guy
Gounko, Natalia V.
Fumagalli, Laura
Fazal, Raheem
Germeys, Christine
Quaegebeur, Annelies
Fendt, Sarah-Maria
Carmeliet, Peter
Verfaillie, Catherine
Van Damme, Philip
Ghesquière, Bart
De Bock, Katrien
Van Den Bosch, Ludo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fa80c26ad33443938150866628a1b0dd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa80c26ad33443938150866628a1b0dd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12099-4
